The bulge region of HIV-1 TAR RNA binds metal ions in solution

Binding of Mg(2+), Ca(2+) and Co(NH(3))(6)(3+) ions to the HIV-1 TAR RNA in solution was analysed by (19)F NMR spectroscopy, metal ion-induced RNA cleavages and Brownian dynamics (BD) simulations. Chemically synthesised 29mer oligoribonucleotides of the TAR sequence labelled with 5-fluorouridine (FU...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Olejniczak, Mikołaj, Gdaniec, Zofia, Fischer, Artur, Grabarkiewicz, Tomasz, Bielecki, Łukasz, Adamiak, Ryszard W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2002
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12364603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf541
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