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The bulge region of HIV-1 TAR RNA binds metal ions in solution
Binding of Mg(2+), Ca(2+) and Co(NH(3))(6)(3+) ions to the HIV-1 TAR RNA in solution was analysed by (19)F NMR spectroscopy, metal ion-induced RNA cleavages and Brownian dynamics (BD) simulations. Chemically synthesised 29mer oligoribonucleotides of the TAR sequence labelled with 5-fluorouridine (FU...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140541/ https://ncbi.nlm.nih.gov/pubmed/12364603 |
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