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Basal transcriptional regulation of human damage-specific DNA-binding protein genes DDB1 and DDB2 by Sp1, E2F, N-myc and NF1 elements

The human DDB1 and DDB2 genes encode the 127 and 48 kDa subunits, respectively, of the damage-specific DNA-binding protein (DDB). Mutations in the DDB2 gene have been correlated with the hereditary disease xeroderma pigmentosum group E. We have investigated the proximal promoters of the DDB genes, b...

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Autori principali: Nichols, Anne F., Itoh, Toshiki, Zolezzi, Francesca, Hutsell, Stephanie, Linn, Stuart
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC140516/
https://ncbi.nlm.nih.gov/pubmed/12527763
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