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Basal transcriptional regulation of human damage-specific DNA-binding protein genes DDB1 and DDB2 by Sp1, E2F, N-myc and NF1 elements

The human DDB1 and DDB2 genes encode the 127 and 48 kDa subunits, respectively, of the damage-specific DNA-binding protein (DDB). Mutations in the DDB2 gene have been correlated with the hereditary disease xeroderma pigmentosum group E. We have investigated the proximal promoters of the DDB genes, b...

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Udgivet i:Nucleic Acids Res
Principais autores: Nichols, Anne F., Itoh, Toshiki, Zolezzi, Francesca, Hutsell, Stephanie, Linn, Stuart
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140516/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12527763/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg152
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