Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA

RNA interference (RNAi) is a RNA-mediated sequence-specific gene silencing mechanism. Recently, this mechanism has been used to down-regulate protein expression in mammalian cells by applying synthetic- or vector-generated small interfering RNAs (siRNAs). However, for the evaluation of this new knoc...

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Bibliographic Details
Main Authors: Czauderna, Frank, Fechtner, Melanie, Aygün, Hüseyin, Arnold, Wolfgang, Klippel, Anke, Giese, Klaus, Kaufmann, Jörg
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC140507/
https://ncbi.nlm.nih.gov/pubmed/12527776
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