Antisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translation

Initiation of protein synthesis on the hepatitis C virus (HCV) mRNA involves a structured element corresponding to the 5′ untranslated region and constituting an internal ribosome entry site (IRES). The domain IIId of the HCV IRES, an imperfect RNA hairpin extending from nucleotides 253 to 279 of th...

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Bibliografske podrobnosti

izdano v:	Nucleic Acids Res
Principais autores:	Tallet-Lopez, Béatrice, Aldaz-Carroll, Lydia, Chabas, Sandrine, Dausse, Eric, Staedel, Cathy, Toulmé, Jean-Jacques
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 2003
Teme:	Articles
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12527783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg139
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