Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains

Plant homeodomain (PHD) domains are found in >400 eukaryotic proteins, many of which are transcriptional regulators. Naturally occurring point mutations or deletions of this domain contribute to a variety of human diseases, including ATRX syndrome, myeloid leukemias and autoimmune dysfunction. He...

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Main Authors: Capili, Allan D., Schultz, David C., Rauscher, Frank J., Borden, Katherine L.B.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC140198/
https://ncbi.nlm.nih.gov/pubmed/11226167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.1.165
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