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Cysteine-rich LIM domains of LIM-homeodomain and LIM-only proteins contain zinc but not iron.

The structure of LIM domains has major implications for transcription because proteins such as Is1-1 contain two LIM domains associated with a homeodomain, and RBTN1/Ttg-1 and RBTN2/Ttg-2 contain two LIM domains but no homeodomain. Conserved cysteine and histidine residues in the LIM domains suggest...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Archer, V E, Breton, J, Sanchez-Garcia, I, Osada, H, Forster, A, Thomson, A J, Rabbitts, T H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42938/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7904068/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.316
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