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Cysteine-rich LIM domains of LIM-homeodomain and LIM-only proteins contain zinc but not iron.

The structure of LIM domains has major implications for transcription because proteins such as Is1-1 contain two LIM domains associated with a homeodomain, and RBTN1/Ttg-1 and RBTN2/Ttg-2 contain two LIM domains but no homeodomain. Conserved cysteine and histidine residues in the LIM domains suggest...

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Main Authors: Archer, V E, Breton, J, Sanchez-Garcia, I, Osada, H, Forster, A, Thomson, A J, Rabbitts, T H
格式: Artigo
語言:Inglês
出版: 1994
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC42938/
https://ncbi.nlm.nih.gov/pubmed/7904068
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