Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
The peripheral anionic site on acetylcholinesterase (AChE), located at the active center gorge entry, encompasses overlapping binding sites for allosteric activators and inhibitors; yet, the molecular mechanisms coupling this site to the active center at the gorge base to modulate catalysis remain u...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140045/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12505979/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg005 |
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