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Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site

The peripheral anionic site on acetylcholinesterase (AChE), located at the active center gorge entry, encompasses overlapping binding sites for allosteric activators and inhibitors; yet, the molecular mechanisms coupling this site to the active center at the gorge base to modulate catalysis remain u...

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Bibliografiska uppgifter
Huvudupphovsmän: Bourne, Yves, Taylor, Palmer, Radić, Zoran, Marchot, Pascale
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC140045/
https://ncbi.nlm.nih.gov/pubmed/12505979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg005
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