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Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site

The peripheral anionic site on acetylcholinesterase (AChE), located at the active center gorge entry, encompasses overlapping binding sites for allosteric activators and inhibitors; yet, the molecular mechanisms coupling this site to the active center at the gorge base to modulate catalysis remain u...

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Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Bourne, Yves, Taylor, Palmer, Radić, Zoran, Marchot, Pascale
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140045/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12505979/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg005
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