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Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?
BACKGROUND: Sodium/iodide symporter (NIS) is a key protein in iodide transport by thyroid cells and this activity is a prerequisite for effective radioiodide treatment of thyroid cancer. In the majority of thyroid cancers, however, iodide uptake is reduced, probably as a result of decreased NIS prot...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139985/ https://ncbi.nlm.nih.gov/pubmed/12475396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-2-35 |
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