Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?

BACKGROUND: Sodium/iodide symporter (NIS) is a key protein in iodide transport by thyroid cells and this activity is a prerequisite for effective radioiodide treatment of thyroid cancer. In the majority of thyroid cancers, however, iodide uptake is reduced, probably as a result of decreased NIS prot...

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Pubblicato in:	BMC Cancer
Autori principali:	Chiefari, Eusebio, Brunetti, Antonio, Arturi, Franco, Bidart, Jean-Michel, Russo, Diego, Schlumberger, Martin, Filetti, Sebastiano
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2002
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12475396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2407-2-35
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