Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?

BACKGROUND: Sodium/iodide symporter (NIS) is a key protein in iodide transport by thyroid cells and this activity is a prerequisite for effective radioiodide treatment of thyroid cancer. In the majority of thyroid cancers, however, iodide uptake is reduced, probably as a result of decreased NIS prot...

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Publié dans:	BMC Cancer
Auteurs principaux:	Chiefari, Eusebio, Brunetti, Antonio, Arturi, Franco, Bidart, Jean-Michel, Russo, Diego, Schlumberger, Martin, Filetti, Sebastiano
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2002
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12475396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2407-2-35
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