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Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?

BACKGROUND: Sodium/iodide symporter (NIS) is a key protein in iodide transport by thyroid cells and this activity is a prerequisite for effective radioiodide treatment of thyroid cancer. In the majority of thyroid cancers, however, iodide uptake is reduced, probably as a result of decreased NIS prot...

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Udgivet i:BMC Cancer
Principais autores: Chiefari, Eusebio, Brunetti, Antonio, Arturi, Franco, Bidart, Jean-Michel, Russo, Diego, Schlumberger, Martin, Filetti, Sebastiano
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2002
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12475396/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2407-2-35
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