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Stereoselective α-fluoroamide and α-fluoro-γ-lactone synthesis by an asymmetric zwitterionic aza-Claisen rearrangement

BACKGROUND: Asymmetric introduction of fluorine α-to a carbonyl has become popular recently, largely because the direct fluorination of enolates by asymmetric electrophilic fluorinating reagents has improved, and as a result such compounds are becoming attractive synthons. We have sought an alternat...

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Autori principali: Tenza, Kenny, Northen, Julian S, O'Hagan, David, Slawin, Alexandra M Z
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1399461/
https://ncbi.nlm.nih.gov/pubmed/16542024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1860-5397-1-13
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