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Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases

Protein aggregation and the formation of highly insoluble amyloid structures is associated with a range of debilitating human conditions, which include Alzheimer's disease, Parkinson's disease, and the Creutzfeldt–Jakob disease. Muscle acylphosphatase (AcP) has already provided significant insights...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Chiti, Fabrizio, Calamai, Martino, Taddei, Niccolò, Stefani, Massimo, Ramponi, Giampietro, Dobson, Christopher M.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139903/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12374855/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.212527999
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