Cooperativity between DNA Methyltransferases in the Maintenance Methylation of Repetitive Elements

We used mouse embryonic stem (ES) cells with systematic gene knockouts for DNA methyltransferases to delineate the roles of DNA methyltransferase 1 (Dnmt1) and Dnmt3a and -3b in maintaining methylation patterns in the mouse genome. Dnmt1 alone was able to maintain methylation of most CpG-poor region...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Liang, Gangning, Chan, Matilda F., Tomigahara, Yoshitaka, Tsai, Yvonne C., Gonzales, Felicidad A., Li, En, Laird, Peter W., Jones, Peter A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139739/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.2.480-491.2002
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