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Cooperativity between DNA Methyltransferases in the Maintenance Methylation of Repetitive Elements
We used mouse embryonic stem (ES) cells with systematic gene knockouts for DNA methyltransferases to delineate the roles of DNA methyltransferase 1 (Dnmt1) and Dnmt3a and -3b in maintaining methylation patterns in the mouse genome. Dnmt1 alone was able to maintain methylation of most CpG-poor region...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139739/ https://ncbi.nlm.nih.gov/pubmed/11756544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.2.480-491.2002 |
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