Cooperativity between DNA Methyltransferases in the Maintenance Methylation of Repetitive Elements

We used mouse embryonic stem (ES) cells with systematic gene knockouts for DNA methyltransferases to delineate the roles of DNA methyltransferase 1 (Dnmt1) and Dnmt3a and -3b in maintaining methylation patterns in the mouse genome. Dnmt1 alone was able to maintain methylation of most CpG-poor region...

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Bibliografische gegevens
Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Liang, Gangning, Chan, Matilda F., Tomigahara, Yoshitaka, Tsai, Yvonne C., Gonzales, Felicidad A., Li, En, Laird, Peter W., Jones, Peter A.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 2002
Onderwerpen:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139739/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.2.480-491.2002
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Cooperativity between DNA Methyltransferases in the Maintenance Methylation of Repetitive Elements

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