Cooperativity between DNA Methyltransferases in the Maintenance Methylation of Repetitive Elements

We used mouse embryonic stem (ES) cells with systematic gene knockouts for DNA methyltransferases to delineate the roles of DNA methyltransferase 1 (Dnmt1) and Dnmt3a and -3b in maintaining methylation patterns in the mouse genome. Dnmt1 alone was able to maintain methylation of most CpG-poor region...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Εκδόθηκε σε:	Mol Cell Biol
Κύριοι συγγραφείς:	Liang, Gangning, Chan, Matilda F., Tomigahara, Yoshitaka, Tsai, Yvonne C., Gonzales, Felicidad A., Li, En, Laird, Peter W., Jones, Peter A.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis 2002
Θέματα:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139739/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.2.480-491.2002
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