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hpr1Δ Affects Ribosomal DNA Recombination and Cell Life Span in Saccharomyces cerevisiae

Multiple genetic pathways have been shown to regulate life span and aging in the yeast Saccharomyces cerevisiae. Here we show that loss of a component of the RNA polymerase II complex, Hpr1p, results in a decreased life span. Although hpr1Δ mutants have an increased rate of recombination within the...

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Hlavní autoři: Merker, Robert J., Klein, Hannah L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC139738/
https://ncbi.nlm.nih.gov/pubmed/11756539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.2.421-429.2002
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