hpr1Δ Affects Ribosomal DNA Recombination and Cell Life Span in Saccharomyces cerevisiae

Multiple genetic pathways have been shown to regulate life span and aging in the yeast Saccharomyces cerevisiae. Here we show that loss of a component of the RNA polymerase II complex, Hpr1p, results in a decreased life span. Although hpr1Δ mutants have an increased rate of recombination within the...

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Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autori principali:	Merker, Robert J., Klein, Hannah L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2002
Soggetti:	DNA Dynamics and Chromosome Structure
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139738/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756539/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.2.421-429.2002
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