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hpr1Δ Affects Ribosomal DNA Recombination and Cell Life Span in Saccharomyces cerevisiae

Multiple genetic pathways have been shown to regulate life span and aging in the yeast Saccharomyces cerevisiae. Here we show that loss of a component of the RNA polymerase II complex, Hpr1p, results in a decreased life span. Although hpr1Δ mutants have an increased rate of recombination within the...

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Udgivet i:Mol Cell Biol
Principais autores: Merker, Robert J., Klein, Hannah L.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139738/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756539/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.2.421-429.2002
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