hpr1Δ Affects Ribosomal DNA Recombination and Cell Life Span in Saccharomyces cerevisiae

Multiple genetic pathways have been shown to regulate life span and aging in the yeast Saccharomyces cerevisiae. Here we show that loss of a component of the RNA polymerase II complex, Hpr1p, results in a decreased life span. Although hpr1Δ mutants have an increased rate of recombination within the...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Merker, Robert J., Klein, Hannah L.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2002
Matèries:	DNA Dynamics and Chromosome Structure
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139738/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756539/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.2.421-429.2002
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