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Age-Dependent Poliovirus Replication in the Mouse Central Nervous System Is Determined by Internal Ribosome Entry Site-Mediated Translation

Mouse cells are not permissive for the replication of human rhinovirus type 2 (HRV2). To determine the role of the HRV2 internal ribosome entry site (IRES) in determining species specificity, a recombinant poliovirus (P1/HRV2) was constructed by substituting the poliovirus IRES with the IRES from HR...

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Bibliographic Details
Main Authors: Kauder, Steven, Kan, Sherry, Racaniello, Vincent R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395422/
https://ncbi.nlm.nih.gov/pubmed/16501069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.6.2589-2595.2006
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