Attenuation of Rabies Virus Replication and Virulence by Picornavirus Internal Ribosome Entry Site Elements

Gene expression of nonsegmented negative-strand RNA viruses is regulated at the transcriptional level and relies on the canonical 5′-end-dependent translation of capped viral mRNAs. Here, we have used internal ribosome entry sites (IRES) from picornaviruses to control the expression level of the pho...

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Detalhes bibliográficos
Main Authors: Marschalek, Adriane, Finke, Stefan, Schwemmle, Martin, Mayer, Daniel, Heimrich, Bernd, Stitz, Lothar, Conzelmann, Karl-Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643788/
https://ncbi.nlm.nih.gov/pubmed/19073737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02055-08
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