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Borna Disease Virus Replication in Organotypic Hippocampal Slice Cultures from Rats Results in Selective Damage of Dentate Granule Cells

In the hippocampus of Borna disease virus (BDV)-infected newborn rats, dentate granule cells undergo progressive cell death. BDV is noncytolytic, and the pathogenesis of this neurodevelopmental damage in the absence of immunopathology remains unclear. A suitable model system to study early events of...

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Detalhes bibliográficos
Main Authors: Mayer, Daniel, Fischer, Heike, Schneider, Urs, Heimrich, Bernd, Schwemmle, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212617/
https://ncbi.nlm.nih.gov/pubmed/16140749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.11716-11723.2005
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