Tissue-Specific Replicating Capacity of a Chimeric Poliovirus That Carries the Internal Ribosome Entry Site of Hepatitis C Virus in a New Mouse Model Transgenic for the Human Poliovirus Receptor

Nucleotides (nt) 108 to 742 of an infectious cDNA clone of poliovirus (PV) Mahoney strain, including the corresponding region of the internal ribosome entry site (IRES), was replaced by nt 28 to 710 of hepatitis C virus (HCV) cDNA corresponding to the whole HCV IRES. A chimeric PV (2A-369) was gener...

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Main Authors: Yanagiya, Akiko, Ohka, Seii, Hashida, Noriyasu, Okamura, Masahito, Taya, Choji, Kamoshita, Nobuhiko, Iwasaki, Kuniko, Sasaki, Yukari, Yonekawa, Hiromichi, Nomoto, Akio
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC228512/
https://ncbi.nlm.nih.gov/pubmed/12970433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.19.10479-10487.2003
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