A Chromatin Insulator-Like Element in the Herpes Simplex Virus Type 1 Latency-Associated Transcript Region Binds CCCTC-Binding Factor and Displays Enhancer-Blocking and Silencing Activities

A previous study demonstrated that the latency-associated transcript (LAT) promoter and the LAT enhancer/reactivation critical region (rcr) are enriched in acetyl histone H3 (K9, K14) during herpes simplex virus type 1 (HSV-1) latency, whereas all lytic genes analyzed (ICP0, UL54, ICP4, and DNA poly...

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Bibliographic Details
Main Authors: Amelio, Antonio L., McAnany, Peterjon K., Bloom, David C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395413/
https://ncbi.nlm.nih.gov/pubmed/16474142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.5.2358-2368.2006
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