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Retroviral Restriction Factors Fv1 and TRIM5α Act Independently and Can Compete for Incoming Virus before Reverse Transcription

The restriction factors Fv1 and TRIM5α provide dominant blocks to retroviral infection, targeting incoming capsids at a postentry, preintegration step. They both restrict N-tropic murine leukemia virus with similar specificity yet act at different points in the viral life cycle. TRIM5α-restricted vi...

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Autors principals: Passerini, Luca D., Keckesova, Zuzana, Towers, Greg J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395401/
https://ncbi.nlm.nih.gov/pubmed/16474118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.5.2100-2105.2006
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