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Differential Restriction of Human Immunodeficiency Virus Type 2 and Simian Immunodeficiency Virus SIVmac by TRIM5α Alleles

Primate lentiviruses have narrow host ranges, due in part to their sensitivities to mammalian intracellular antiviral factors such as APOBEC3G and TRIM5α. Despite the protection provided by this innate immune system, retroviruses are able to transfer between species where they can cause disease. Thi...

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Detalhes bibliográficos
Main Authors: Ylinen, Laura M. J., Keckesova, Zuzana, Wilson, Sam J., Ranasinghe, Srinika, Towers, Greg J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212619/
https://ncbi.nlm.nih.gov/pubmed/16140735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.11580-11587.2005
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