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TRIM5 Acts as More Than a Retroviral Restriction Factor
The retrovirus restriction factor TRIM5α blocks post-entry infection of retroviruses in a species-specific manner. As a cellular E3 ubiquitin ligase, TRIM5α binds to the retroviral capsid lattice in the cytoplasm of an infected cell and accelerates the uncoating process of retroviral capsid, thus pr...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Molecular Diversity Preservation International (MDPI)
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159411/ https://ncbi.nlm.nih.gov/pubmed/21866272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v3071204 |
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