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Genetic reduction of chronic muscle pain in mice lacking calcium/calmodulin-stimulated adenylyl cyclases

BACKGROUND: The Ca(2+)/calmodulin-stimulated adenylyl cyclase (AC) isoforms AC1 and AC8, couple NMDA receptor activation to cAMP signaling pathways in neurons and are important for development, learning and memory, drug addiction and persistent pain. AC1 and AC8 in the anterior cingulate cortex (ACC...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vadakkan, Kunjumon I, Wang, Hansen, Ko, Shanelle W, Zastepa, Evelyn, Petrovic, Michele J, Sluka, Kathleen A, Zhuo, Min
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395303/
https://ncbi.nlm.nih.gov/pubmed/16503978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-2-7
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