Engagement of CD160 receptor by HLA-C is a triggering mechanism used by circulating natural killer (NK) cells to mediate cytotoxicity

Circulating human natural killer (NK) lymphocytes have been functionally defined by their ability to exert cytotoxic activity against MHC class I-negative target cell lines, including K562. Therefore, it was proposed that NK cells recognized the “missing self.” We show here that the Ig-like CD160 re...

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Bibliografske podrobnosti
Main Authors: Le Bouteiller, Philippe, Barakonyi, Aliz, Giustiniani, Jérome, Lenfant, Françoise, Marie-Cardine, Anne, Aguerre-Girr, Maryse, Rabot, Magali, Hilgert, Ivan, Mami-Chouaib, Fathia, Tabiasco, Julie, Boumsell, Laurence, Bensussan, Armand
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC139252/
https://ncbi.nlm.nih.gov/pubmed/12486241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012681099
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