Blister fluid T lymphocytes during toxic epidermal necrolysis are functional cytotoxic cells which express human natural killer (NK) inhibitory receptors

Toxic epidermal necrolysis (TEN) is a rare life-threatening adverse drug reaction characterized by a massive destruction of the epidermis. Immunohistological studies of skin biopsies of TEN showed infiltrates of predominantly CD8(+) T lymphocytes even though other authors reported a prominent involv...

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Dettagli Bibliografici
Autori principali: Le Cleach, L, Delaire, S, Boumsell, L, Bagot, M, Bourgault-Villada, I, Bensussan, A, Roujeau, J C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2000
Soggetti:
Skin Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905549/
https://ncbi.nlm.nih.gov/pubmed/10606987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01119.x
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