A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor

Angiogenesis plays an essential role in several diseases of the eye and in the growth of solid tumors, but existing antiangiogenic therapies have limited benefits in several cases. We report the antiangiogenic effects of a monoclonal antibody, CL1-R2, in several animal models of neovascularization....

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Autors principals: Chabot, Sophie, Jabrane-Ferrat, Nabila, Bigot, Karine, Tabiasco, Julie, Provost, Alexandra, Golzio, Muriel, Noman, Muhammad Zaeem, Giustiniani, Jérôme, Bellard, Elisabeth, Brayer, Stéphanie, Aguerre-Girr, Maryse, Meggetto, Fabienne, Giuriato, Sylvie, Malecaze, François, Galiacy, Stéphane, Jaïs, Jean-Philippe, Chose, Olivier, Kadouche, Jean, Chouaib, Salem, Teissié, Justin, Abitbol, Marc, Bensussan, Armand, Le Bouteiller, Philippe
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092350/
https://ncbi.nlm.nih.gov/pubmed/21482699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100810
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