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CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia

B-cell chronic lymphocytic leukemia (CLL) expresses CD160, a glycosylphosphatidylinositol-linked receptor found on normal natural killer (NK) and T cells, but not B cells. CD160 is a multifunctional molecule in normal lymphocytes, but its role in CLL biology is unknown. In vitro, CLL cells undergo r...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Liu, Feng-Ting, Giustiniani, Jerome, Farren, Timothy, Jia, Li, Bensussan, Armand, Gribben, John G., Agrawal, Samir G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292590/
https://ncbi.nlm.nih.gov/pubmed/20164468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-239483
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