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HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim

Depletion of CD4(+) T cells is the hallmark of HIV infection and AIDS progression. In addition to the direct killing of the viral-infected cells, HIV infection also leads to increased apoptosis of predominantly uninfected bystander cells. This is mediated in part through the HIV-1 Tat protein, which...

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Bibliografski detalji
Glavni autori: Chen, Dan, Wang, Michael, Zhou, Sharleen, Zhou, Qiang
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC139103/
https://ncbi.nlm.nih.gov/pubmed/12486001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf683
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