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The hepatitis C virus 3′-untranslated region or a poly(A) tract promote efficient translation subsequent to the initiation phase

Enhancement of eukaryotic messenger RNA (mRNA) translation initiation by the 3′ poly(A) tail is mediated through interaction of poly(A)-binding protein with eukaryotic initiation factor (eIF) 4G, bridging the 5′ terminal cap structure. In contrast to cellular mRNA, translation of the uncapped, non-p...

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Bibliografski detalji
Glavni autori: Bradrick, Shelton S., Walters, Robert W., Gromeier, Matthias
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1388098/
https://ncbi.nlm.nih.gov/pubmed/16510853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl019
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