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Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression

MicroRNAs (miRNAs) regulate gene expression post-transcriptionally through binding specific sites within the 3′ untranslated regions (UTRs) of their target mRNAs. Numerous investigations have documented repressive effects of miRNAs and identified factors required for their activity. However, the pre...

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Détails bibliographiques
Auteurs principaux: Walters, Robert W., Bradrick, Shelton S., Gromeier, Matthias
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802033/
https://ncbi.nlm.nih.gov/pubmed/19934229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1795410
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