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Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression

MicroRNAs (miRNAs) regulate gene expression post-transcriptionally through binding specific sites within the 3′ untranslated regions (UTRs) of their target mRNAs. Numerous investigations have documented repressive effects of miRNAs and identified factors required for their activity. However, the pre...

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Bibliografski detalji
Glavni autori: Walters, Robert W., Bradrick, Shelton S., Gromeier, Matthias
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802033/
https://ncbi.nlm.nih.gov/pubmed/19934229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1795410
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