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Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression

MicroRNAs (miRNAs) regulate gene expression post-transcriptionally through binding specific sites within the 3′ untranslated regions (UTRs) of their target mRNAs. Numerous investigations have documented repressive effects of miRNAs and identified factors required for their activity. However, the pre...

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Detalhes bibliográficos
Main Authors: Walters, Robert W., Bradrick, Shelton S., Gromeier, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802033/
https://ncbi.nlm.nih.gov/pubmed/19934229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1795410
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