Are Trp53 rescue of Brca1 embryonic lethality and Trp53/Brca1 breast cancer association related?
Brca1 is involved in multiple biological pathways including DNA damage repair, transcriptional regulation, and cell-cycle progression. A complex pattern of interactions of Brca1 with Trp53 has also emerged. Xu and coworkers found that haploid loss of Trp53 significantly reduces the embryonic lethali...
Guardat en:
| Publicat a: | Breast Cancer Res |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11879563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr422 |
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