Founder BRCA1/BRCA2/PALB2 pathogenic variants in French-Canadian breast cancer cases and controls

Abstract Inherited germline pathogenic variants are responsible for ~5% of breast cancer globally. Through rapid expansion and isolation since immigration in the early 17th century, French Canadians are a relatively genetically homogenous founder population and therefore represent a unique demograph...

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Bibliografische Detailangaben

Hauptverfasser:	Supriya Behl, Nancy Hamel, Manon de Ladurantaye, Stéphanie Lepage, Réjean Lapointe, Anne-Marie Mes-Masson, William D. Foulkes
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2020-04-01
Schriftenreihe:	Scientific Reports
Online-Zugang:	https://doi.org/10.1038/s41598-020-63100-w
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