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Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells

BACKGROUND: Pulmonary arterial hypertension is a proliferative vascular disease, characterized by aberrant regulation of smooth muscle cell proliferation and apoptosis in distal pulmonary arteries. Prostacyclin (PGI(2)) analogues have anti-proliferative effects on distal human pulmonary artery smoot...

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Detalhes bibliográficos
Main Authors: Growcott, Ellena J, Spink, Karen G, Ren, Xiaohui, Afzal, Saliha, Banner, Kathy H, Wharton, John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386664/
https://ncbi.nlm.nih.gov/pubmed/16423283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-9
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