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Role of phosphodiesterases in modulation of BK(Ca) channels in hypertensive pulmonary arterial smooth muscle

BK(Ca) channels regulate pulmonary arterial pressure, and protein kinase C (PKC) inhibits BK(Ca) channels, but little is known about PKC-mediated modulation of BK(Ca) channel activity in pulmonary arterial smooth muscle. Studies were done to determine mechanisms of PKC modulation of BK(Ca) channel a...

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Main Authors: Zhu, Shu, White, Richard E., Barman, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019332/
https://ncbi.nlm.nih.gov/pubmed/19124364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753465808091327
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