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Theophylline attenuates Ca(2+) sensitivity and modulates BK channels in porcine tracheal smooth muscle
1. Theophylline, a nonselective phosphodiesterase inhibitor, has long been regarded as a major bronchodilator in the treatment of human asthma. Using front-surface fluorometry with fura-2 and α-toxin permeabilization, the effects of theophylline on intracellular Ca(2+) concentration ([Ca(2+)](i)), t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574100/ https://ncbi.nlm.nih.gov/pubmed/14517178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705508 |
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