Vasorelaxation and inhibition of the voltage-operated Ca(2+) channels by FK506 in the porcine coronary artery

1. Using fura-2 fluorometry, the effects of FK506, an immunosuppressant, on changes in cytosolic Ca(2+) concentrations ([Ca(2+)](i)) and tension were investigated in porcine coronary arterial strips. The effects of FK506 on the activity of voltage-operated Ca(2+) channels were examined by applying a...

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Detalhes bibliográficos
Main Authors: Yasutsune, Toru, Kawakami, Nozomi, Hirano, Katsuya, Nishimura, Junji, Yasui, Hisataka, Kitamura, Kenji, Kanaide, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565846/
https://ncbi.nlm.nih.gov/pubmed/10188984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702339
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