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Anti-proliferative effects of O-acyl-low-molecular-weight heparin derivatives on bovine pulmonary artery smooth muscle cells

Heparin (HP) inhibits the growth of several cell types in vitro including bovine pulmonary artery (BPA) smooth muscle cells (SMCs). In initial studies we discovered that an O-hexanoylated low-molecular-weight (LMW) HP derivative having acyl groups with 6-carbon chain length was more potent inhibitor...

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Detalhes bibliográficos
Main Authors: Garg, Hari G., Mrabat, Hicham, Yu, Lunyin, Hales, Charles A., Li, Boyangzi, Moore, Casey N., Zhang, Fuming, Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234589/
https://ncbi.nlm.nih.gov/pubmed/21773727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-011-9341-6
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