Prion and doppel proteins bind to granule cells of the cerebellum
We reported that expression of the cellular prion protein (PrP(C)) rescues doppel (Dpl)-induced cerebellar degeneration in mice. To search for protein(s) that mediate this process, we fused the C-termini of mouse (Mo) PrP and Dpl to the Fc portion of an IgG. Although both MoPrP-Fc and MoDpl-Fc bound...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2002
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138603/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12446843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.242611999 |
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